NIHR BTRU in Donor Health and Genomics - Events
Seminars take place in the seminar rooms at Strangeways Research Laboratory, 2 Worts' Causeway, Cambridge CB1 8RN
For further information please contact firstname.lastname@example.org
Monday, 4 February 2019 13:00 - 14:00
Topic: The RESTORE (Recovery and Survival of Stem Cell Originated Red Cells) clinical trial
“There are a small number of patients with rare blood group types for whom NHS Blood and Transplant (NHSBT) cannot meet the transfusion requirements. New red blood cells can be grown from human blood stem cells in the laboratory. This trial will assess, in healthy volunteers, the recovery and survival of a mini-dose of red blood cells derived from CD34+cells isolated from adult blood vs standard donated red blood cells. We hope that this will provide us with a novel transfusion product for these patients in the future, some of whom require regular transfusions throughout life (e.g. for thalassemia or sickle cell disease).”
Dr Cédric Ghevaert, Consultant Haematologist at NHSBT and Senior Lecturer in Transfusion Medicine (University of Cambridge). His research focuses on the production of blood cells from pluripotent stem cells with the declared aim to produce novel cellular therapies for transfusion to patients. He has a keen interest in inherited platelet disorders (such as Thrombocytopenia with Absent Radii) using the pluripotent stem cell technology for disease modelling.
Dr Rebecca Cardigan, Head of Components Development at NHSBT and Lecturer in Haematology (University of Cambridge). Her main areas of scientific interest relate to the laboratory and clinical evaluation of major changes to blood component production and methods used to assess blood component quality.
Thursday, 14 March 2019 19:00 - 20:00
Written in Blood: What can blood cells tell us about health and disease?
In the UK, 1.1m people donate blood annually, directly saving lives through transfusion—but, blood can do so much more. Emanuele Di Angelantonio, Professor of Blood Donor Health, Dr Will Astle, Parsa Akbari and Lisa Schmunk discuss how blood donors contribute to the health of everyone in the population by participating in studies which link environmental and genetic factors with properties of the blood. These studies help us understand the role of blood in diseases such as heart attack and stroke. This research is conducted by the National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics, in partnership with NHS Blood and Transplant (NHSBT), to advance the field of blood donor health and research. A short discussion (Q&A period) will follow the talk.
Venue: Mill Lane Lecture Rooms, 8 Mill Lane, Cambridge CB2 1RW
Image Copyright: Karl-Ludwig Poggemann, Electron Microscopy Facility at The National Cancer Institute at Frederick (CC BY 2.0). The name of the Facility was removed from the image.
Wednesday, 20 March 2019 13:00 - 14:00
Topic: Tiered Consent: Optimising consent for for blood donors taking part in research
Dr Jenni Burt, Senior Research Associate (University of Cambridge) and Senior Social Scientist (THIS Institute)
Dr Natasha Kriznik, Research Associate (University of Cambridge and THIS Institute)
Sunday, 24 March 2019 11:00 - 16:00
How can blood donations be used in research?
The BTRU in Donor Health and Genomics works closely with NHS Blood and Transplant to maintain stocks of blood whilst looking after donor health. This has been achieved through studies such as INTERVAL (frequency of blood donation) and COMPARE (methods for measuring haemoglobin).
Join us for fun, hands-on activities to learn more about the blood donation process, blood groups and what our scientists are discovering to benefit the health of the UK population.
Venue: Cambridge Academy for Science and Technology, Robinson Way, Cambridge CB2 0SZ
Monday, 20 May 2019 13:00 - 14:00
Dr Brian Custer, Blood Systems Research Institute
Brian Custer is the Director of Epidemiology and Policy Science at BSRI San Francisco, Vice President of Research and Scientific Affairs at BloodSystems and an Adjunct Professor in the Department of Laboratory Medicine at UCSF. He conducts research on the epidemiology and health economics of the blood supply and transfusion medicine policy throughout the world, primarily focused on infectious diseases, donor health and recipient outcomes.
Friday, 21 June 2019 13:00 - 14:00
Dr Paul Auer, University of Wisconsin-Milwaukee
Dr Auer’s primary research is focused on discovering the genetic determinants of common chronic diseases including heart disease, bleeding disorders, type II diabetes, stroke and colorectal cancer. Specifically, he develops and implements statistical and computational tools for analysing genetic data from large US health studies. He is currently studying the extent to which rare genetic variation influences disease risk in diverse US populations.
Saturday, 13 October 2018 10:00 - 16:00
BTRU Past Event
Hills Road Sixth Form College – Big Biology Day
The Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics is dedicated to discoveries and advances in the field of blood research. Join us at Hills Road Sixth Form College to find out about blood groups, the blood donation process and what we’re learning to benefit the health of the UK population. We will be exhibiting with the BTRU in Organ Donation and Transplantation.
Big Biology Day (BBD) Cambridge is one of the biggest, free biology public engagements events in the country. It brings together the Cambridge biology community and national biology organisations to engage the public in our subject. Big Biology Day
Monday, 26 November 2018 13:00 - 14:00
BTRU Past Event
Topic: Iron depletion in high school-age blood donors: what do we know, and what should we do about it?
Recent research shows that many blood donors have intermediate or advanced iron depletion, with the latest data indicating a greater susceptibility for iron depletion in donors 16 to 18 years old. In this talk, Dr Spencer will review the impact of blood donation on blood donor iron status, motivation for concerns in younger donors, and the operational and regulatory considerations attendant to potential mitigation measures.
Dr Bryan Spencer, American Red Cross
Dr Spencer is a research scientist with an extensive background in epidemiology / public health, infectious disease, study design, management, data analysis and blood safety issues, including in an international context.
Thursday, 13 December 2018 13:00 - 14:00
BTRU Past Event
Topic: Sickle cell disease: when simple meets complex
Sickle cell disease is a simple monogenic blood disorder, yet it is characterized by extreme clinical heterogeneity. In this talk, I will describe how we are using modern complex trait genetic and functional genomic approaches to better understand the genetic causes of this heterogeneity. I will also present recent work focused on the functional characterization of genetic variation associated with blood-cell phenotypes.
Dr Guillaume Lettre, Université de Montréal
Dr Lettre is an associate professor of medicine at the Montreal Heart Institute and the Université de Montréal. His lab uses human genetic and functional genomic approaches to understand the causes of cardiovascular and hematological diseases.