Wellcome Sanger Institute

The Wellcome Sanger Institute, which focuses on understanding the relevance of genetics to health and disease, is Europe’s leading and largest genome campus (~1000 staff) and in receipt of >£300 million in core research funding since 2010.

 

Professor Nicole Soranzo

Senior Group Leader in Human Complex Traits at the Wellcome Sanger Institute

BTRU Theme 1 Lead (Determinants of donation-related biomarkers)

Professor Soranzo was trained in quantitative population and statistical genetics at the University of Milano, University of Dundee and University College London, where she applied genetic analysis to evolutionary studies of natural populations and human traits. She spent two years in the pharmaceutical industry in the US, applying human genetics to improve drug discovery and pharmacogenomics. She returned to the UK at the Sanger Institute, where she started her group in 2009. In 2013 she became adjunct faculty in the School of Clinical Medicine, University of Cambridge, and in 2015 was awarded a personal chair in Human Genetics.

Professor Soranzo studies how the human genome influences the risk of common diseases in the general UK population. She is a member of the University of Cambridge Platelet Biology and Cardiovascular Groups, the EU BLUEPRINT and EpiGeneSys projects and the National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics.

 

Dr Dragana Vuckovic

Postdoctoral Fellow at the Wellcome Sanger Institute

Dr Vuckovic completed her PhD in Statistical Genetics at the University of Trieste in Italy, after graduating in mathematics. Her past and present work aims at developing and applying robust statistical methodology to unravel genetic predisposition to human disease and traits. During her PhD she developed original statistical methods as well as computational genetics frameworks contributing to ground-breaking genetics association studies in large-scale datasets.

Her current research is within Theme 1 of the NIHR-funded BTRU in Donor Health and Genomics, focusing on determinants of donation-related biomarkers. She is building a dataset of putative causative genetic variants for approximately 70 blood measurements and plans to use it to evaluate functional characteristics as well as the ability to predict disease states based on genetic information.